Project CEEX MATNANTECH - 48/2006
MULTIFUNCTIONAL NANOCOMPOSITES BASED ON SUPRAMOLECULAR ARCHITECTURES EXHIBITING OPTOELECTRONIC, PHOTOCHEMICAL, ELECTROCHEMICAL AND BIOLOGICAL PROPERTIES PRECURSORS FOR ADVANCED MATERIALS.
"MAVOPTEL"
The scientific partnership was set up between research and development institutes and universities with different domains of interest, having the purpose of connecting to the priorities and high objectives of European research interests regarding multifunctional advanced materials.
Coordinator: Institute of Chemistry -Timisoara of Romanian Academy
Project Director: Dr. chim. Otilia COSTISOR
Scientific Respondent: Dr. ing. Eugenia FAGADAR-COSMA
Partner 1: Technical University of Cluj-Napoca
Respondent: Prof. Dr. Elena MARIA PICA
Partner 2: Institute of Physical Chemistry "Ilie Murgulescu" - Bucuresti
Respondent: Dr. chim. Luminita PATRON
Partner 3: West University of Timisoara
Respondent: Conf. Dr. ing. Otilia BIZEREA
Partner 4: Research & Development National Institute for Isotopic and Molecular
Technology - Cluj-Napoca
Respondent: Dr. Gheorghe MIHAILESCU
Partner 5: "Politehnica" University of Timisoara
Respondent: Conf. Dr. ing. Gheorghe FAGADAR-COSMA
Abstract:
The purpose of this project is the research and implementation of new materials, composites and state-of-the-art techniques in the targeted domains, which, in their diversity, are bounded by their central element: the synthesis and utilizations of porphyrinic macrocycles. These are molecules capable of drastically changing or adjusting their properties by reconfiguring the electron distribution of the aromatic ring in order to develop supramolecular structures, thus allowing the accomplishment of some strategic objectives related to the development of fundamental sciences (physics and chemistry), nanotechnologies, highly strategically technology domains (photovoltaic cells), safety and durability for building engineering (corrosion inhibition), monitoring the quality of the environment (electrochemical sensors) and competitive health treatments (PDT therapy of cancer). The porphyrin molecules will be assembled by different means (electrode-deposition, immobilization in polymeric membranes, functionalization etc.), as supramolecular architectures. Within these architectures, the porphyrins will transfer a great amount of their intrinsic properties towards the new advanced materials, but in the same time, new opto-electric properties will be generated which enables their use in medicine and technology. The project present novelty both regarding the obtainment of new materials and in their applicability domains and is contributing to the increase of knowledge in fundamental chemistry.
The main proposed objectives:
- the study of the obtainment and the optimized synthesis of meso-tetraphenylporphyrinic chromophores divers-substituted with inductive donor groups and of their complexes with transitional metals;
- synthesis and physico-chemical characterization of biliary salt - transitional metal complexes; characterization of thermal stability of the compounds exhibiting biological activity.
- porphyrin functionalization with gold nanoparticles and characterization by cyclic voltametry and UV-vis spectroscopy;
- the synthesis of supramolecular structures of meso-tetraphenylporphyrin peripherally divers substituted and of their metallic complexes with tris(bipiridyl)ruthenium, as sensibility enhancers for photovoltaic cells;
- the study, development and testing of photochemically-active supramolecular devices by porphyrins or metalloporphyrins deposition on crystalline TiO2 support; conductibility measurements; building the experimental model of a photovoltaic cell with a Zn-complex porphyrinic light-capturing material;
- the formulation of metalloporphyrin-based sensitive membranes for new sensors with selectivity for iodide, fluoride, thiocyanate or heavy metals; building functional devices and monitoring life and food quality as well as the degree of pollution in the environment;
- determining and using the corrosion inhibition effect of porphyrinic compounds onto the metallic structures used in building engineering, in order to increase their chemical resistance and their life span;
- development of non-intrusive cancer treatment by testing porphyrins and their Cu and Zn complexes in malign cell cultures;
- theoretical studies about molecular modeling of biliary salt - transitional metal compounds and the structure-properties correlation (QSPR) and the structure-biological activity correlation (QSAR);
- investigations regarding the citotoxic and antiproliferative effect over tumoral cells.
